Efficient activation of carboxyl polysaccharides for the preparation of conjugates

  • Farkaš P
  • Bystrický S
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Abstract

We demonstrated here a highly efficient activation of carboxyl groups applicable to any polysaccharide. It was done by using the alternative activation agent, 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride. More specifically, we prepared glucans bearing linkers of different lengths that possessed masked carbonyl groups. © 2006 Elsevier Ltd. All rights reserved.

Author-supplied keywords

  • Conjugation
  • DMTMM
  • Glucan

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