An efficient construction of quinazolin-4 (3H)-ones under microwave irradiation

  • Li F
  • Feng Y
  • Meng Q
 et al. 
  • 14

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Abstract

The highly accelerated Niementowski synthesis of quinazolin-4(3H)-one and quinazolin-2,4- dione derivatives under microwave irradiation is reported. Compared to the conventional conditions, this new method shows the advantages of a good substrate tolerance, and a clean and rapid conversion. The method has been successfully applied for the construction of the key intermediate of iressa

Author-supplied keywords

  • -ones
  • 3h
  • iressa
  • microwave irradiation
  • quinazolin-4

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Authors

  • Feng Li

  • Yiqing Feng

  • Qingqing Meng

  • Wenhua Li

  • Zhiming Li

  • Quanrui Wang

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