(from the chapter) Clinical electrophysiology offers a variety of powerful and informative methods for studying cerebral function and dysfunction after traumatic brain injury (TBI). Electroencephalography (EEG) was the first clinical diagnostic tool to provide evidence of abnormal brain function due to TBI. Such early observations led to the development of more sophisticated electrophysiological techniques, including quantitative EEG (QEEG), topographic QEEG (also known as brain electrical activity mapping, or BEAM), evoked potentials (EPs), event-related potentials (ERPs), and magnetoencephalography (MEG) and magnetic source imaging (MSI). Each of these techniques provides a means of measuring brain activity noninvasively and with temporal resolution vastly superior to that achieved with any of the several presently available functional neuroimaging methods. This chapter is intended to provide a broad overview of the principles of clinical electrophysiology and a brief discussion of some of the more interesting and potentially important findings from studies of electrodiagnostic techniques in traumatically brain-injured individuals. The basic principles of electrophysiological recording are presented first, followed by a brief discussion of each of the electrophysiological recording techniques noted above. Because a complete review of all findings of relevance to the neuropsychiatry of TBI is beyond the scope of the present work, the remainder of this chapter focuses on the applications and limitations of recently developed electrophysiological techniques to the evaluation, treatment, or study of this population. (PsycINFO Database Record (c) 2010 APA, all rights reserved).
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