Emerging approaches in the molecular design of receptor-selective peptide ligands: conformational, topographical and dynamic considerations

  • Hruby V
  • al-Obeidi F
  • Kazmierski W
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Abstract

A review, with 107 refs., of the design of peptide and protein ligands (hormones) with specific phys., chem., and biol. properties. Specific topics discussed were conformational constraint, structure-biol. activities relations, and rational drugs as well as topog. design possibilities and prospects. [on SciFinder(R)]

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Authors

  • V J Hruby

  • F al-Obeidi

  • W Kazmierski

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