Enantiospecific Synthesis of Carbocyclic Aminoimidazole Carboxamide Ribonucleotide (C-Aicar), Succinoaminoimidazole Carboxamide Ribonucleotide (C-Saicar), and a New Intermediate for Saicar Analogs

  • Schmitt L
  • Caperelli C
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Abstract The (-)-enantiomer of the carbocyclic analogs of aminoimidazole carboxamide ribonucleotide (C-AICAR1, 7), and succinoaminoimidazole carboxamide ribonucleotide (C-SAICAR, 14) have been prepared. En route, a new intermediate (19) for the preparation of SAICAR analogs was developed.

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  • Laurent Schmitt

  • Carol A. Caperelli

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