Engineering Protein Switches: Sensors, Regulators, and Spare Parts for Biology and Biotechnology

  • Golynskiy M
  • Koay M
  • Vinkenborg J
 et al. 
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Abstract

Switch protein switch! Proteins that switch between distinct conformational states are ideal for monitoring and controlling molecular processes in biological systems. We discuss new engineering concepts for the construction of protein switches that have the potential to be generally applicable and discuss them according to their mechanism of action. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Author-supplied keywords

  • Allosterism
  • Biosensors
  • Molecular switches
  • Protein design
  • Protein engineering
  • Synthetic biology

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