Eosinophil-rich inflammatory response to FloSeal hemostatic matrix presenting as postoperative pelvic pain

Abstract

FloSeal hemostatic matrix has been reported to be effective for the control of intraoperative bleeding in various surgeries. We report 3 patients who experienced a possible allergic response to FloSeal with the formation of excessive granulation tissue and fibrosis that were associated with early postoperative pelvic pain that led to additional surgical intervention. © 2009 Mosby, Inc. All rights reserved.