Epidemiology of pancreatic cancer and the role of family history

  • Olson S
  • Kurtz R
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Pancreatic cancer is a lethal disease for which only a small number of risk factors have been identified. In addition to older age, male gender, and black race, risk factors include smoking, obesity, long-standing diabetes and pancreatitis, and heavy alcohol use; allergies such as hay fever are related to lowered risk. Several genetic syndromes increase risk of pancreatic cancer. Work on more common genetic variants promises to reveal more potentially important genetic associations. J. Surg. Oncol. 2013;107:1-7. © 2012 Wiley Periodicals, Inc.

Author-supplied keywords

  • BRCA1 protein
  • BRCA2 protein
  • Peutz Jeghers syndrome
  • alcohol consumption
  • asthma
  • cancer epidemiology
  • cancer incidence
  • cancer mortality
  • cancer patient
  • cancer registry
  • cancer risk
  • cyclin dependent kinase inhibitor 2A
  • diabetes mellitus
  • endoscopic echography
  • endoscopic retrograde cholangiopancreatography
  • familial atypical multiple mole melanoma syndrome
  • familial colon polyposis
  • family history
  • gender
  • gene
  • gene mutation
  • genetic association
  • genetic polymorphism
  • genetic susceptibility
  • genetic variability
  • germ line
  • hereditary breast and ovarian cancer syndrome
  • hereditary nonpolyposis colorectal cancer
  • high risk patient
  • human
  • intraductal papillary mucinous tumor
  • mismatch repair
  • obesity
  • pancreas adenoma
  • pancreas cancer
  • pancreatitis
  • partner and localizer of BRCA2 gene
  • pollen allergy
  • priority journal
  • protein MLH1
  • protein MSH2
  • protein MSH6
  • race
  • review
  • smoking
  • tumor suppressor gene

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  • S H Olson

  • R C Kurtz

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