Estimulación basada en mindfulness en la enfermedad de Alzheimer avanzada: Ensayo clínico piloto comparativo de equivalencia. = Mindfulness-based stimulation in advanced Alzheimer's disease: A comparative, non-inferiority, clinical pilot study.

  • Quintana Hernández D
  • Miró Barrachina M
  • Fernández I
 et al. 
  • 4


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


Introduction: A longitudinal study was conducted in order to analyze the feasibility, safety, and effects of the practice of mindfulness, relaxation and cognitive stimulation on the evolution of Alzheimer’s disease, with the aim of testing the equivalence of these interventions. Material and methods: There were a total of 168 participants with probable Alzheimer’s disease (AD) treated with donepezil. In the present article, the 21 participants with advanced AD who completed a follow-up period of 24 months are presented. The participants were grouped into three experimental groups (mindfulness, relaxation, and cognitive stimulation) and one control group. Each group carried out three weekly sessions with bi-annual follow-up measurements (cognition: CAMCOG and MMSE; functionality: RDRS; psychopathology: NPI). Non-parametric analyses were performed. Results: The cognitive function and functionality scores showed no significant differences between the groups. However, the scores in cognitive function of the mindfulness group and the cognitive stimulation group did not decrease in an intra-group analysis. In NPI, there were significant differences between the mindfulness group and the control group by the end of the study (P

Author-supplied keywords

  • 2015
  • Alzheimer's Disease
  • Alzheimer’s disease
  • Cognition
  • Cognitive Therapy
  • Functional status
  • Mindfulness
  • Psychopathology
  • Relaxation

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in


  • Domingo Jesús Quintana Hernández

  • María Teresa Miró Barrachina

  • Ignacio Ibáñez Fernández

  • Angelo Santana del Pino

  • Jaime Rojas Hernández

  • Javier Rodríguez García

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free