Evaluation of the Orthogonal Projection on Latent Structure Model Limitations Caused by Chemical Shift Variability and Improved Visualization of Biomarker Changes in 1H NMR Spectroscopic Metabonomic Studies

Olivier Cloarec †, † M. E. D., Johan Trygg, ‡, Andrew Craig, †, † R. H. B., † J. C. L., … Holmes†, E. (2005). Evaluation of the Orthogonal Projection on Latent Structure Model Limitations Caused by Chemical Shift Variability and Improved Visualization of Biomarker Changes in 1H NMR Spectroscopic Metabonomic Studies. Analytical Chemistry, 77(2), 517–526.