Evolution of protein complexes by duplication of homomeric interactions

  • Pereira-Leal J
  • Levy E
  • Kamp C
 et al. 
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Abstract

Cellular functions are accomplished by the concerted actions of functional modules. The mechanisms driving the emergence and evolution of these modules are still unclear. Here we investigate the evolutionary origins of protein complexes, modules in physical protein-protein interaction networks.

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Authors

  • Jose B. Pereira-Leal

  • Emmanuel D. Levy

  • Christel Kamp

  • Sarah A. Teichmann

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