Expanding the soil antibiotic resistome: exploring environmental diversity

  • D'Costa V
  • Griffiths E
  • Wright G
  • 244


    Mendeley users who have this article in their library.
  • 144


    Citations of this article.


Antibiotic resistance has largely been studied in the context of failure of the drugs in clinical settings. There is now growing evidence that bacteria that live in the environment (e.g. the soil) are multi-drug-resistant. Recent functional screens and the growing accumulation of metagenomic databases are revealing an unexpected density of resistance genes in the environment: the antibiotic resistome. This challenges our current understanding of antibiotic resistance and provides both barriers and opportunities for antimicrobial drug discovery. © 2007 Elsevier Ltd. All rights reserved.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Vanessa M. D'Costa

  • Emma Griffiths

  • Gerard D. Wright

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free