The expression of genes encoding enzymes regulating fat metabolism is affected by maternal nutrition when lambs are fed algae high in omega-3

  • Alvarenga T
  • Chen Y
  • Lewandowski P
 et al. 
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The current study investigated the effects of the supplementation of lambs with algae on the expression of genes that direct the accumulation of long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA). The nutrition of the lamb's dam around mating was also considered. The dams were fed with either silage (SLG) or oat/cottonseed (OAT) based diets for six weeks prior to and, three weeks following conception. mRNA levels of FADS1, FADS2, CPT1, SCD, ACC and fad2 were measured in the liver, muscle and subcutaneous fat from lambs fed a control diet consisting of oat and lupin grains and chopped lucerne (CTRL) or the CTRL diet with algae (DHAgold™) added at 1.92% DM (ALG). The lambs were 117.4±2.4 days of age and weighed 37.3±3.2 kg at the beginning of the experimental period, and six weeks later they were slaughtered at 160.4±2.4 days of age and a final live weight of 50.1±4.4 kg. The expression of FADS1 in liver tissue was not affected (P>0.05) by the interaction between dam nutrition and algae supplementation, however it was higher (P0.05) by algae supplementation, but it was higher (P0.05).

Author-supplied keywords

  • Dam nutrition
  • Docosahexaenoic acid
  • Eicosapentaenoic acid
  • Fatty acid desaturase
  • Sheep
  • Stearoyl-CoA desaturase

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  • Tharcilla Isabella Rodrigues Costa Alvarenga

  • Yizhou Chen

  • Paul Lewandowski

  • Eric N. Ponnampalam

  • Shahzad Sediq

  • Edward H. Clayton

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