Extracorporeal life support in the acute management of tumour lysis syndrome

  • A.D. P
  • K. M
  • T.R. K
 et al. 
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Abstract

A 16-month old boy presented with a severe tumour lysis syndrome (TLS) complicating induction therapy for acute myeloid leukaemia. This was further complicated by a respiratory syncytial virus infection. The failure of response to escalating treatment necessitated the use of extracorporeal life support (ECLS) during continuation of his induction chemotherapy. He was weaned from support after the resolution of the TLS and completed chemotherapy successfully. ECLS may have a role to play in the acute support of children with cardiorespiratory failure as a result of malignancy or the required treatment. 2012 The Author 2012. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

Author-supplied keywords

  • *extracorporeal oxygenation
  • *tumor lysis syndrome/si [Side Effect]
  • *tumor lysis syndrome/th [Therapy]
  • acute granulocytic leukemia/di [Diagnosis]
  • acute granulocytic leukemia/dt [Drug Therapy]
  • acute kidney failure/th [Therapy]
  • antineoplastic agent/ae [Adverse Drug Reaction]
  • antineoplastic agent/dt [Drug Therapy]
  • antineoplastic agent/tl [Intrathecal Drug Administ
  • article
  • bone marrow examination
  • cancer chemotherapy
  • case report
  • child
  • child health care
  • clinical feature
  • cytarabine/ae [Adverse Drug Reaction]
  • cytarabine/dt [Drug Therapy]
  • daunorubicin/ae [Adverse Drug Reaction]
  • daunorubicin/dt [Drug Therapy]
  • disease severity
  • drug effect
  • drug safety
  • drug treatment failure
  • etoposide/ae [Adverse Drug Reaction]
  • etoposide/dt [Drug Therapy]
  • human
  • induction chemotherapy
  • leukocyte count
  • male
  • multiple organ failure/si [Side Effect]
  • multiple organ failure/th [Therapy]
  • percutaneous drainage
  • pericardial effusion/co [Complication]
  • pericardial effusion/su [Surgery]
  • preschool child
  • priority journal
  • respiratory failure/th [Therapy]
  • thrombocyte count
  • thrombocytopenia/co [Complication]
  • treatment duration
  • vascular access

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Authors

  • Prabhu A.D.

  • Mos K.

  • Karl T.R.

  • Anderson B.

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