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Journal article

F-18-FDG uptake in tuberculosis

Bakheet S, Powe J, Ezzat A, Rostom A ...see all

CLINICAL NUCLEAR MEDICINE, vol. 23, issue 11 (1998) pp. 739-742 Published by LIPPINCOTT WILLIAMS & WILKINS

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Abstract

Two patients are described who showed abnormal fluorine-18
fiuorodeoxyglucose (F-18 FDG) uptake that was due to benign disease,
specifically tuberculous lymphadenitis and pneumonitis. The first
patient had ulceration and oozing of the left nipple that was related to
Paget's disease. An F-18 FDG PET, whole-body scan, which was performed
for staging, showed no breast uptake. However, there was intense
multifocal uptake in mediastinal, supraclavicular, and para-aortic areas
that was confirmed radiologically to represent widespread
lymphadenopathy. Pathologic examination of a mediastinal lymph node
showed active tuberculosis. The second patient showed intense focal F-18
FDG uptake in mediastinal and supraclavicular areas and para-aortic
lymphadenopathy due to non-Hodgkin's lymphoma. In addition, there was
abnormal F-18 FDG lung uptake that revealed the presence of acid-fast
bacilli on bronchial ravage. Intense focal F-18 FDG uptake in widespread
lymphadenopathy or in the lung could be caused by infectious diseases
such as tuberculosis. This possibility should be considered when
whole-body scans of patients with cancer are interpreted, especially in
those with a high incidence of infectious disease.

Author-supplied keywords

  • tuberculous lymphadenitis and pneumonitis; F-18 FD

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Authors

  • S M B Bakheet

  • J Powe

  • A Ezzat

  • A Rostom

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