OBJECTIVE: To compare the factors affecting sexual function in premenopausal women with type 2 diabetes using the female sexual function index (FSFI). DESIGN: Cross-sectional study. SETTING: Premenopausal women with type 2 diabetes and healthy volunteers in an academic research environment. PATIENT(S): Sixty-two type 2 diabetic women were compared with 50 controls. The FSFI scores of the patients were compared according to age, duration of diabetes, marriage, socioeconomic status, parity, menstruation regularity, body mass index (BMI), and smoking. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Female sexual function index scores. RESULT(S): The mean FSFI score in diabetics was lower than in controls. Menstrual irregularity and duration of diabetes affected female sexual function unlike age, BMI, socioeconomic status, duration of marriage, or parity. Regularly menstruating women had higher FSFI scores (27.1 +/- 6.7) than irregularly menstruating women (20.7 +/- 7.4). Type 2 diabetics were divided into three groups according to duration of diabetes. The women having diabetes longer than 10 years had the worse sexual function. Also, smoking affected inversely female sexual well being. CONCLUSION(S): Menstrual disturbance, smoking, and longer duration of diabetes (more than 10 years) impair FSFI scores in premenopausal women with type 2 diabetes.
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