fastsimcoal: Manual

  • Excoffier L
  • Foll M
  • 46

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Abstract

MOTIVATION: Genetic studies focus on increasingly larger genomic regions of both extant and ancient DNA, and there is a need for simulation software to match these technological advances. We present here a new coalescent-based simulation program fastsimcoal, which is able to quickly simulate a variety of genetic markers scattered over very long genomic regions with arbitrary recombination patterns under complex evolutionary scenarios. Availability and Implementation: fastsimcoal is a C++ program compiled for Windows, MacOsX and Linux platforms. It is freely available at cmpg.unibe.ch/software/fastsimcoal/, together with its detailed user manual and example input files.

Author-supplied keywords

  • 10
  • 1093
  • 1334
  • 27 no
  • 9 2011
  • bioinformatics
  • btr124
  • doi
  • genetics and population analysis
  • informatics applications note
  • pages 1332
  • vol

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Authors

  • Laurent Excoffier

  • Matthieu Foll

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