Features of obsessive-compulsive disorder in patients primarily diagnosed with schizophrenia

  • Ohta M
  • Kokai M
  • Morita Y
  • 25


    Mendeley users who have this article in their library.
  • 58


    Citations of this article.


We investigated the prevalence of obsessive-compulsive disorder (OCD) among patients who were primarily diagnosed with schizophrenia. We investigated the differences in the neuropsychiatric features and motor symptoms between patients with schizophrenia who did or did not have OCD. Seventy-one subjects with the DSM-IV diagnosis of schizophrenia were evaluated by the Structured Clinical Interview for DSM-IV Axis I Disorders, the Yale-Brown Obsessive-compulsive Scale and the Positive and Negative Syndrome Scale. To assess their motor symptoms, the Abnormal Involuntary Movements Scale, the Barnes rating scale for drug-induced akathisia and the Simpson and Angus extrapyramidal symptoms (EPS) rating scale were used. The 13 subjects with OCD (18.3%) had significantly more severe motor symptoms than the non-OCD subjects. Patients with schizophrenia who exhibit moderate to severe motor symptoms as side-effects of neuroleptics, should be examined for OCD comorbidity. Patients who are found to have OCD comorbidity must be treated with carefully chosen medications, including serotonin re-uptake inhibitors.

Author-supplied keywords

  • Motor symptom
  • Obsessive-compulsive disorder
  • Schizophrenia
  • Yale-Brown Obsessive-compulsive Scale (Y-BOCS)

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Masayuki Ohta

  • Masahiro Kokai

  • Yoshio Morita

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free