A finite element model for epidermal wound healing is proposed. The model takes into account the sequential steps of angiogenesis (neo-vascularization) and wound contraction (the actual healing of a wound). An innovation in the present study is the combination of both partially overlapping processes, yielding novel insights into the process of wound healing. The models consist of nonlinearly coupled diffusion-reaction equations, in which transport of oxygen, growth factors and epidermal cells and mitosis are taken into account.
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