Fixation methods for electron microscopy of human and other liver

  • Wisse E
  • Braet F
  • Duimel H
 et al. 
  • 59

    Readers

    Mendeley users who have this article in their library.
  • 43

    Citations

    Citations of this article.

Abstract

For an electron microscopic study of the liver, expertise and complicated, time-consuming processing of hepatic tissues and cells is needed. The interpretation of electron microscopy (EM) images requires knowledge of the liver fine structure and experience with the numerous artifacts in fixation, embedding, sectioning, contrast staining and microscopic imaging. Hence, the aim of this paper is to present a detailed summary of different methods for the preparation of hepatic cells and tissue, for the purpose of preserving long-standing expertise and to encourage new investigators and clinicians to include EM studies of liver cells and tissue in their projects.

Author-supplied keywords

  • Biopsy
  • Electron microscopy
  • Liver
  • Perfusion
  • Tissue fixation

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free