A free-radical cascade methylation/cyclization of N -arylacrylamides and isocyanides with dicumyl peroxide

  • Xu Z
  • Yan C
  • Liu Z
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Abstract

A free-radical cascade methylation/cyclization of a wide range of N-arylacrylamides and isocyanides is demonstrated by using dicumyl peroxide as the methylating reagent, which provides a convenient and selective access to various methylated N-heterocycles such as oxindoles and phenanthridines.

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Authors

  • Zhengbao Xu

  • Chaoxian Yan

  • Zhong Quan Liu

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