Full-field quantitative phase imaging by white-light interferometry with active phase stabilization and its application to biological samples

  • Li X
  • Yamauchi T
  • Iwai H
 et al. 
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Abstract

(Doc. ID 68025) We report a Koehler-illumination-based full-field, actively stabilized, low-coherence phase-shifting interfer-ometer, which is built on a white-light Michelson interferometer. By using a phase-stepping technique we can obtain full-field phase images of the sample. An actively stabilized phase-lock circuit is employed in the system to reduce phase noise. An application to human epithelial cells (HeLa cells) is achieved in our ex-periment. The advancement of this technique rests in its ability to take images of unstained biological samples quantitatively and on a nanometer scale.

Author-supplied keywords

  • 1203180
  • OCIS codes

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Authors

  • Xinhong Li

  • Toyohiko Yamauchi

  • Hidenao Iwai

  • Yutaka Yamashita

  • Haijun Zhang

  • Teruo Hiruma

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