Functional group-selective poisoning of molecular catalysts: A ruthenium cluster-catalysed highly amide-selective silane reduction that does not affect ketones or esters

Abstract

The addition of amines eliminates the catalytic activity of a triruthenium cluster in the hydrosilane reduction of ketones and esters without affecting the rate of reduction of amides; selective reduction of the amide group in amido ketones and amido esters is accomplished. © The Royal Society of Chemistry.