Galactooligosaccharides reduce infection caused by Listeria monocytogenes and modulate IgG and IgA levels in mice

  • Sangwan V
  • Tomar S
  • Ali B
 et al. 
  • 9


    Mendeley users who have this article in their library.
  • 2


    Citations of this article.


The effect of galactooligosaccharides (GOS) on infection caused by Listeria monocytogenes and levels of immunoglobulins (IgG and IgA) was studied in mice. β-Galactosidase extracted from native strains of Streptococcus thermophilus was used for GOS production. Seventy two mice were divided in to four groups; normal control group (NCG), pathogenic control group (PCG), and test groups 1 and 2. NCG and PCG were fed with standard rodent diet and the remaining groups were fed with standard diet supplemented with GOS (6% of diet). Six mice from each group were sacrificed on days 2, 5 and 8 post-challenge. Lower counts of L.monocytogenes were observed in the intestine, liver and spleen of groups fed with GOS. Feeding of GOS augmented the IgA (small intestine) and IgG (blood) concentration in mice. Findings of the study indicate that GOS have potential to modulate the immune system along with a protective effect against L.monocytogenes.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text


  • Vikas Sangwan

  • Sudhir K. Tomar

  • Babar Ali

  • Ram R.B. Singh

  • Ashish K. Singh

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free