GENEHUNTER: Your 'one-stop shop' for statistical genetic analysis?

  • Nyholt D
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Abstract

The past decade has brought a proliferation of statistical genetic (linkage) analysis techniques, incorporating new methodology and/or improvement of existing methodology in gene mapping, specifically targeted towards the localization of genes underlying complex disorders. Most of these techniques have been implemented in user-friendly programs and made freely available to the genetics community. Although certain packages may be more 'popular' than others, a common question asked by genetic researchers is 'which program is best for me?'. To help researchers answer this question, the following software review aims to summarize the main advantages and disadvantages of the popular GENEHUNTER package.

Author-supplied keywords

  • GENEHUNTER
  • Linkage
  • Linkage disequilibrium
  • Model-based linkage analysis
  • Model-free multipoint linkage analysis
  • Quantitative trait loci
  • Transmission disequilibrium test
  • Variance components analysis

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Authors

  • Dale R. Nyholt

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