Generating microbubbles in a co-flowing microfluidic device

  • Wang K
  • Xie L
  • Lu Y
 et al. 
  • 16


    Mendeley users who have this article in their library.
  • 10


    Citations of this article.


This paper introduces an experimental study on the microbubble generation mechanism in a co-flowing microfluidic device. Using propane, butane and air as the dispersed phases and different SDS-PEG solutions as the continuous phases, two kinds of bubble generating phenomena, named "single-bubble generation" flow and "dual-bubble generation" flow, were observed in experiment and uniform bubbles with average diameters ranging from 391. μm to 713. μm and polydispersity less than 2.9% were successfully prepared. The pressure fluctuation of gas phase is carefully analyzed with the Young-Laplace equation and the bubble generation mechanism is summarized from the dynamic movement of gas-liquid interface. The main factors impacting the bubble size variation are illustrated for both the organic and inorganic gases. A universal correlation is established to predict the average bubble diameters. © 2013 Elsevier Ltd.

Author-supplied keywords

  • Co-flowing microchannel
  • Gas-liquid interface
  • Generation mechanism
  • Microbubble
  • Organic and inorganic gases
  • Pressure fluctuation

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Kai Wang

  • Lisi Xie

  • Yangcheng Lu

  • Guangsheng Luo

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free