Genetic modeling of primary tooth emergence: A study of Australian twins

  • Bockmann M
  • Hughes T
  • Townsend G
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The aim of this study was to quantify contributions of genetic and environmental factors to variation in timing of emergence of the primary teeth in a sample of monozygotic and dizygotic twins, using univariate model-fitting approaches. The sample comprised 94 pairs of monozygotic twins and 125 pairs of dizygous twins, all of European ancestry, aged from 2-6 years. Tooth emergence timing was based on parental report, with a subset of data validated by clinical assessment. Heritability estimates for tooth emergence timing were generally high, around 90%, however estimates for the lower right lateral incisor and the lower canines were around 50%. These findings confirm a strong genetic influence on observed variation in the timing of emergence of the human primary teeth.

Author-supplied keywords

  • Development
  • Genetics
  • Humans
  • Teeth

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  • Michelle R. Bockmann

  • Toby E. Hughes

  • Grant C. Townsend

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