Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. A total of 25.8 million people-8.3% of the population-have diabetes. Oxidation reaction to produce free radicals of oxygen that cause cellular damage of critical biological molecules such as proteins, lipids, and DNA is one of the most important factors in the development of chronic diseases in recent years. When damaged cell molecules do not repair and oxidation degradation continues, there is a high risk of chronic diseases and cancer. The ability of antioxidants to react with free radicals can prevent the destructive effects of these radicals and the chronic diseases. Tomato is a good source of many nutrients and metabolites required for human health: several minerals, vitamins C and E, β-carotene, lycopene, flavonoids, organic acids, phenolics, and chlorophyll. This study reviewed a number of studies to investigate the role of tomatoes and other substances on type 2 diabetes.
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