Growth responses of Cassia obtusifolia toward human intestinal bacteria

  • Sung B
  • Kim M
  • Lee W
 et al. 
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Abstract

1,2-Dihydroxyanthraquinone (1) was isolated from the seed of Cassia obtusifolia through bioassay-guided fractionation. 1,2-Dihydroxyanthraquinone strongly inhibited the growth of Clostridium perfringens and Escherichia coli. Structure-activity relationship revealed that 1,4-dihydroxyanthraquinone (2) and 1,8-dihydroxyanthraquinone (3) had strong growth-inhibition against C. perfringens. In growth-promoting activity, 1,2-, 1,4-, and 1,8- dihydroxyanthraquinones exhibited strong growth-promoting activity to Bifidobacterium bifidum. © 2004 Elsevier B.V. All rights reserved.

Author-supplied keywords

  • 1,2-Dihydroxyanthraquinone
  • Anthraquinones
  • Cassia obtusifolia
  • Growth response
  • Intestinal bacteria

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Authors

  • Bo Kyung Sung

  • Moo Key Kim

  • Wang Hyu Lee

  • Dong Heon Lee

  • Hoi Seon Lee

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