Gynecomasty: estrogen and androgen receptors. A clinical-pathological investigation.

  • Poulsen H
  • Hermansen C
  • Andersen J
 et al. 
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Abstract

The histology, estrogen (ER)- and androgen (AR)- receptor content, s-FSH, s-LH, s-17-beta-estradiol, U-17-ketosteroid and U-17-ketogenic steroid patterns were measured in a consecutive series of 20 patients operated on for gynecomasty. Two out of 22 specimens were ER-positive, and 4 out of 22 were AR-positive. No relationship was demonstrated between the histopathologic features, ie. active-intermediate-inactive gynecomasty, and the steroid receptor content in the present limited number of cases. In addition, there was no marked relationship between the histopathologic features and the hormone values.

Author-supplied keywords

  • 17-Hydroxycorticosteroids
  • 17-Hydroxycorticosteroids: analysis
  • 17-Ketosteroids
  • 17-Ketosteroids: analysis
  • Adolescent
  • Adult
  • Aged
  • Androgen
  • Androgen: analysis
  • Estradiol
  • Estradiol: analysis
  • Estrogen
  • Estrogen: analysis
  • Follicle Stimulating Hormone
  • Follicle Stimulating Hormone: analysis
  • Gynecomastia
  • Gynecomastia: metabolism
  • Gynecomastia: pathology
  • Humans
  • Luteinizing Hormone
  • Luteinizing Hormone: analysis
  • Male
  • Middle Aged
  • Receptors

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  • ISSN: 0108-0164
  • SCOPUS: 2-s2.0-0022180991
  • PUI: 16250008
  • PMID: 3931411
  • SGR: 0022180991

Authors

  • H S Poulsen

  • C Hermansen

  • J A Andersen

  • H U Andersen

  • J Jensen

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