Helicobacter pylori seropositivity in patients with hyperemesis gravidarum

  • Shaban M
  • Kandil H
  • Elshafei A
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Abstract

Objective: The aim of this study was to analyze the hypothesis that there was an association between hyperemesis gravidarum (HG) and Helicobacter pylori (HP) infection. Methods: The study group consisted of 95 pregnant women with HG and 116 asymptomatic pregnant women who were admitted to our hospital between January 1997 and October 1998. Specific serum immunoglobulin G for HP was assayed in the sera of the study group after informed consent was obtained. Chi-square and Student's t-test were used accordingly for statistical analysis of the data. Results: Serologically positive HP infection was detected in 87 of the 95 patients with HG (91.5%) whereas 52 of the 116 asymptomatic gravidas (44.8%) serving as the control group had positive antibody concentrations against HP. The ratio of HP positivity in pregnant women with HG was significantly higher than asymptomatic pregnant women (P

Author-supplied keywords

  • Egyptian population
  • Helicobacter pylori
  • Hyperemesis gravidarum

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Authors

  • Mona M. Shaban

  • Hisham O. Kandil

  • Arwa H. Elshafei

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