Hemorrhagic enterocolitis and death in two felines (Panthera tigris altaica and Panthera leo) associated with Clostridium perfringens type A.

  • Zhang Y
  • Hou Z
  • Ma J
  • Readers

    Mendeley users who have this article in their library.
  • Citations

    Citations of this article.


Severe hemorrhagic enterocolitis was observed in a Siberian tiger (Panthera tigris altaica) and a lion (Panthera leo). Both animals developed acute depression, anorexia, and bloody diarrhea several days before death. Small and large intestines were diffusely congested, edematous, necrotic, and filled with hemorrhagic fluid, and mesenteric lymph nodes were enlarged and congested. Pure and abundant growth of gram-positive bacilli was obtained in culture under anaerobic conditions from the livers of both felines. Identification of highly virulent Clostridium perfringens Type A was based on pathologic lesions, hemolytic patterns, morphologic structure, and polymerase chain reaction. Animal inoculation assays indicated that C. perfringens Type A played an important role in the pathogenesis of both felines.

Author-supplied keywords

  • Animals
  • Animals, Zoo
  • Clostridium Infections
  • Clostridium Infections: microbiology
  • Clostridium Infections: pathology
  • Clostridium Infections: veterinary
  • Clostridium perfringens
  • Clostridium perfringens: classification
  • Enterocolitis
  • Enterocolitis: microbiology
  • Enterocolitis: veterinary
  • Fatal Outcome
  • Hemorrhage
  • Hemorrhage: microbiology
  • Hemorrhage: veterinary
  • Lions
  • Tigers

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Yanlong Zhang

  • Zhijun Hou

  • Jianzhang Ma

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free