Hepatocyte Proteomics

Abstract

Proteomics is a discipline of using proteomic technologies to investigate the protein biology. In general, the proteomic analysis has allowed us to have a better understansing about the expression levels, structures and fucntions of proteins in cells or tissues in a high through-put manner. In this review, we briefly discuss general concepts of protemic research and decribe how the frequently used protemic technologies, including mass spectrometry, can be applied to study protein biology of cells or tissues. We also review the recent advances in the studies on the hepatocyte proteomics, since liver diseases, such as viral hepatitis and hepatoma, appears to be relatively common in the Chinese population. Key