Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer

  • Attard G
  • Clark J
  • Ambroisine L
 et al. 
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Abstract

A fluorescence in situ hybridisation (FISH) assay has been used to screen for ETV1 gene rearrangements in a cohort of 429 prostate cancers from patients who had been diagnosed by trans-urethral resection of the prostate. The presence of ETV1 gene alterations (found in 23 cases, 5.4%) was correlated with higher Gleason Score (P=0.001), PSA level at diagnosis (P=

Author-supplied keywords

  • ACSL3
  • ACSL3:ETV1 fusion
  • ETV1
  • Prostate cancer

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