High prevalence of unrelated multidrug-resistant Acinetobacter baumannii isolates in Pakistani military hospitals

  • Evans B
  • Hamouda A
  • Abbasi S
 et al. 
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Abstract

This study examined the antimicrobial resistance properties of 17 Acinetobacter baumannii isolates obtained over 2 months from 2 military hospitals in Rawalpindi, Punjab Province, Pakistan, with a particular focus on carbapenem resistance. Susceptibility testing found that 14 of the 17 A. baumannii isolates were multidrug-resistant, being resistant to either 4 (2 isolates) or 5 (12 isolates) different classes of drugs. Of the A. baumannii isolates, 11 (65%) were resistant to meropenem or imipenem, which was associated with the carriage of a blaOXA-23 gene (P85%. The presence of the blaOXA-23 gene in multiple distantly related A. baumannii isolates suggests that its widespread nature cannot be ascribed to the spread of a dominant clone, but rather to the dissemination of multiple carbapenem-resistant lineages.

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Authors

  • Benjamin EvansNorwich Medical School

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  • Ahmed Hamouda

  • Shahid A. Abbasi

  • Farooq A. Khan

  • Sebastian G.B. Amyes

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