Household air pollution: a call for studies into biomarkers of exposure and predictors of respiratory disease

  • Rylance J
  • Gordon S
  • Naeher L
 et al. 
  • 2


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


Household air pollution (HAP) from indoor burning of biomass or coal is a leading global cause of morbidity and mortality, mostly due to its association with acute respiratory infection in children and chronic respiratory and cardiovascular diseases in adults. Interventions that have significantly reduced exposure to HAP improve health outcomes and may reduce mortality. However, we lack robust, specific, and field-ready biomarkers to identify populations at greatest risk and to monitor the effectiveness of interventions. New scientific approaches are urgently needed to develop biomarkers of human exposure that accurately reflect exposure or effect. In this Perspective, we describe the global need for such biomarkers, the aims of biomarker development, and the state of development of tests that have the potential for rapid transition from laboratory bench to field use.

Author-supplied keywords

  • Acute Disease
  • Air Pollution, Indoor/*analysis
  • Anisoles/analysis
  • Biomarkers/*analysis
  • Carbon Monoxide/analysis
  • Carboxyhemoglobin/analysis
  • DNA Methylation
  • Developing Countries
  • Fires
  • Global Health
  • Glucose/analogs & derivatives/analysis
  • Humans
  • Isoprostanes/analysis
  • Malondialdehyde/analysis
  • Particulate Matter/adverse effects
  • Polycyclic Aromatic Hydrocarbons/analysis
  • Respiratory Tract Diseases/*etiology
  • Respiratory Tract Infections/etiology
  • air pollution
  • biomarkers
  • exposure

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in


  • J Rylance

  • S B Gordon

  • L P Naeher

  • A Patel

  • J R Balmes

  • O Adetona

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free