Abstract
Large numbers of peptides encoded in human short open reading frames have been recently identified but not yet functionally characterized. Results: A peptide interacts with the Ku heterodimer and stimulates nonhomologous end-joining DNA repair. Conclusion: Newly discovered cellular peptides can be functionally characterized by identifying their interaction partners. Significance: Short ORF-encoded polypeptides participate in essential cellular processes. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.
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CITATION STYLE
Slavoff, S. A., Heo, J., Budnik, B. A., Hanakahi, L. A., & Saghatelian, A. (2014). A human short open reading frame (sORF)-Encoded polypeptide that stimulates DNA end joining. Journal of Biological Chemistry, 289(16), 10950–10957. https://doi.org/10.1074/jbc.C113.533968
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