Immunosuppressive activity of ethanolic extract of seeds of Moringa oleifera Lam. in experimental immune inflammation

  • Mahajan S
  • Mehta A
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Ethnopharmacological relevance: Traditionally, the plant Moringa oleifera Lam. (Moringaceae) is used for the treatment of ascites and rheumatism, while the dried seeds of the plant are used as an 'anti-allergic' agent. Aim of the study: The aim of the study was to assess the efficacy of ethanolic extract of seeds from Moringa oleifera Lam. in experimental immune inflammation. Materials and methods: Circulatory and splenic leukocyte counts, delayed-type hypersensitivity reactions and humoral antibody responses were measured in mice using SRBC as the antigen. In addition, macrophage phagocytosis was measured by the carbon clearance test. Results: The extract dose-dependently (50, 100 and 200. mg/kg) inhibited spleen weight as well as circulatory leukocyte and splenocyte counts. The delayed-type hypersensitivity reaction was significantly inhibited (P

Author-supplied keywords

  • Humoral immunity
  • Immune inflammation
  • Immunosuppressive
  • Moringa oleifera

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  • Shailaja G. Mahajan

  • Anita A. Mehta

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