The impact of chronic obstructive pulmonary disease in patients hospitalized for worsening heart failure with reduced ejection fraction: an analysis of the EVEREST Trial

  • Mentz R
  • Schmidt P
  • Kwasny M
 et al. 
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Abstract

Background: Chronic obstructive pulmonary disease (COPD) is prevalent in heart failure (HF) patients, yet these patients are poorly characterized. We aimed to describe the characteristics and outcomes of patients with systolic dysfunction and COPD in a contemporary HF randomized trial. Methods and Results: EVEREST investigated 4,133 patients hospitalized with worsening HF and an ejection fraction (EF)

Author-supplied keywords

  • Adrenergic beta-Antagonists [therapeutic use]
  • Aged[checkword]
  • Angiotensin-Converting Enzyme Inhibitors [therapeu
  • Chronic Obstructive [mortality]
  • Comorbidity
  • Female[checkword]
  • Heart Failure
  • Hospital Mortality
  • Hospitalization
  • Humans[checkword]
  • Kaplan-Meier Estimate
  • Male[checkword]
  • Mineralocorticoid Receptor Antagonists
  • Outcome Assessment (Health Care)
  • Pulmonary Disease
  • Stroke Volume
  • Systolic [drug therapy] [mortality]
  • acetylsalicylic acid
  • aged
  • aldosterone antagonist
  • anticoagulant agent
  • antilipemic agent
  • article
  • beta adrenergic receptor blocking agent
  • beta adrenergic receptor stimulating agent
  • bronchodilating agent
  • calcium channel blocking agent
  • cholinergic receptor blocking agent
  • chronic obstructive lung disease
  • clinical feature
  • comorbidity
  • digoxin
  • dipeptidyl carboxypeptidase inhibitor
  • disease exacerbation
  • diuretic agent
  • female
  • furosemide
  • heart ejection fraction
  • heart failure
  • hospital discharge
  • hospital patient
  • hospitalization
  • human
  • hydralazine
  • inotropic agent
  • male
  • mortality
  • nitrate
  • outcome assessment
  • prevalence
  • priority journal
  • randomized controlled trial (topic)
  • risk assessment
  • risk reduction
  • steroid
  • systolic dysfunction
  • theophylline
  • treatment outcome

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Authors

  • Rj Mentz

  • Ph Schmidt

  • Mj Kwasny

  • Ap Ambrosy

  • Cm O'Connor

  • Ma Konstam

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