Impact of perioperative renal dysfunction in heart transplantation: Combined heart and kidney transplantation could help to reduce postoperative mortality

  • Lee J
  • Lee S
  • Cho H
 et al. 
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Background: Renal dysfunction is a frequent problem in heart failure patients. We aimed to investigate the predictors of mortality after heart transplantation and the impact of perioperative renal dysfunction on short-term and long-term prognosis. Material/Methods: We analyzed the outcomes of patients undergoing isolated heart transplantation (IHT, n=62) and combined heart-kidney transplantation (CHKT, n=5) between October 2007 and May 2012. Among all patients, 55.2% had preoperative renal dysfunction. Results: Compared with the IHT group, the CHKT group had a lower estimated glomerular filtration rate (p=0.001), and higher proportion of diabetes (p=0.008), hypertension (p=0.010), renal failure (p=0.036), and greater incidence of preoperative continuous renal replacement therapy (CRRT) (p=0.025). Despite unfavorable baseline conditions in the CHKT group, there was no postoperative mortality. Early 30-day postoperative mortality only occurred in the IHT group (5 patients, 8.1%). In multivariate analysis, persistent renal dysfunction (HR 29.356, p

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  • [Combined heart and kidney transplantation, Heart

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  • J.M. Lee

  • S.-A. Lee

  • H.-J. Cho

  • H.-M. Yang

  • H.-Y. Lee

  • H.Y. Hwang

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