Implant fixation by bone ingrowth

  • Kienapfel H
  • Sprey C
  • Wilke A
 et al. 
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The term osseointegration referred originally to an intimate
contact of bone tissue with the surface of a titanium implant;
the term bone ingrowth refers to bone formation within an
irregular (beads, wire mesh, casting voids, cut grooves)
surface of an implant. The section dealing with the historical
background describes the development of macroporous,
microporous, and textured surfaces with an emphasis on the
evolution of porous and textured metal surfaces. The principal
requirements for osseointegration and bone ingrowth are
systematically reviewed as follows: i) the physiology of
osseointegration and bone ingrowth, including biomaterial
biocompatibility with respect to cellular and matrix response
at the interface; ii) the implant surface geometry
characteristics; iii) implant micromotion and fixation modes;
and iv) the implant-bone interface distances. Based on current
methods of bone ingrowth assessment, this article
comparatively reviews and discusses the results of
experimental studies with the objective of determining local
and systemic factors that enhance bone ingrowth fixation.

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  • H Kienapfel

  • C Sprey

  • A Wilke

  • P Griss

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