Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines

  • Grundy S
  • Cleeman J
  • Bairey Merz C
 et al. 
  • 1

    Readers

    Mendeley users who have this article in their library.
  • N/A

    Citations

    Citations of this article.

Abstract

The Adult Treatment Panel III (ATP III) of the National Cholesterol Education Program issued an evidence-based set of guidelines on cholesterol management in 2001. Since the publication of ATP III, 5 major clinical trials of statin therapy with clinical end points have been published. These trials addressed issues that were not examined in previous clinical trials of cholesterol-lowering therapy. The present document reviews the results of these recent trials and assesses their implications for cholesterol management. Therapeutic lifestyle changes (TLC) remain an essential modality in clinical management. The trials confirm the benefit of cholesterol-lowering therapy in high-risk patients and support the ATP III treatment goal of low-density lipoprotein cholesterol (LDL-C)

Author-supplied keywords

  • Cholesterol
  • Coronary disease
  • Lipoproteins
  • Trials

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Scott M.t Grundy

  • James I. Cleeman

  • C. Noel Bairey Merz

  • H. Bryan Brewer

  • Luther T. Clark

  • Donald B. Hunninghake

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free