Importance of shear in prosthetic valve closure dynamics.

  • Scotten L
  • Siegel R
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Abstract

The results of recent hematological studies have suggested that, under non-physiological flow conditions, circulating procoagulant proteins activate the coagulation cascade. In the present study, in-vitro estimates of flow transients at or near the time of valve closure, including regional backflow velocity (RBV, m/s), flow acceleration (m/s2), and rate of acceleration (jerk, m/s3), have shed new light on the blood-damage potential of prosthetic valves.

Author-supplied keywords

  • Aortic Valve
  • Heart Valve Prosthesis
  • Mitral Valve
  • Rheology

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  • ISSN: 0966-8519
  • SCOPUS: 2-s2.0-84863004645
  • PUI: 368068717
  • PMID: 22655497
  • SGR: 84863004645

Authors

  • Lawrence N Scotten

  • Rolland Siegel

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