The importance of tricuspid regurgitation and right ventricular overload in ICD/CRT recipients: Beside the left, beyond the left

  • Fazio S
  • Carlomagno G
  • 14


    Mendeley users who have this article in their library.
  • 7


    Citations of this article.


Device therapy for advanced heart failure has become increasingly employed in the last 10 years. Several retrospective studies have postulated a harmful effect of implantable cardioverter-defibrillator (ICD) lead placement on tricuspid valve function and right heart hemodynamics, in particular among patients with preexisting pulmonary vascular overload and both left and right ventricular remodeling/dysfunction. This functional hypothesis is also supported by long-term clinical follow-up analyses of ICD and cardiac resynchronization therapy recipients. In this viewpoint, we propose that the possibility of worsening tricuspid regurgitation and consequent hemodynamic deterioration following device implantation should be considered in future studies, as well as in the preimplant evaluation of individual candidates among other clinical factors. 

Author-supplied keywords

  • cardiac resynchronization
  • implantable cardioverter-defibrillator
  • pulmonary hypertension
  • tricuspid regurgitation

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text


  • Serafino Fazio

  • Guido Carlomagno

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free