Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmia

  • Moss A
  • Hall W
  • Cannom D
 et al. 
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Background Unsustained ventricular tachycardia in patients with previous myocardial infarction and left ventricular dysfunction is associated with a two-year mortality rate of about 30 percent. We studied whether prophylactic therapy with an implanted cardioverter–defibrillator, as compared with conventional medical therapy, would improve survival in this high-risk group of patients. Methods Over the course of five years, 196 patients in New York Heart Association functional class I, II, or III with prior myocardial infarction; a left ventricular ejection fraction

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  • Arthur J. Moss

  • W. Jackson Hall

  • David S. Cannom

  • James P. Daubert

  • Steven L. Higgins

  • Helmut Klein

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