Incidence and Short-Term Prognosis of Transient Ischemic Attack in a Population-Based Study

  • Kleindorfer D
  • Panagos P
  • Pancioli A
 et al. 
  • 1


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


Background and Purpose—Transient ischemic attacks (TIAs) have been shown to be a strong predictor of subsequent stroke and death. We present the incidence and short-term prognosis of TIA within a large population with a significant proportion of minorities with out-of-hospital TIA. Methods—TIA cases were identified between July 1, 1993 and June 30, 1994 from the Greater Cincinnati/Northern Kentucky population of 1.3 million inhabitants by previously published surveillance methods, including inpatient and out-of-hospital events. Incidence rates were adjusted to the 1990 population, and life-table analyses were used for prognosis. Results—The overall race, age, and gender-adjusted incidence rate for TIA within our population was 83 per 100 000, with age, race, and gender adjusted to the 1990 US population. Blacks and men had significantly higher rates of TIA than whites and women. Risk of stroke after TIA was 14.6% at 3 months, and risk of TIA/stroke/death was 25.2%. Age, race, and sex were not associated with recurrent TIA or subsequent stroke in our population, but age was associated with mortality. Conclusions—Using our incidence rates for TIA in blacks and whites, we conservatively estimate that Ϸ240 000 TIAs occurred in 2002 in the United States. Our incidence rate of TIA is slightly higher than previously reported, which may be related to the inclusion of blacks and out-of-hospital events. There are racial and gender-related differences in the incidence of TIA. We found a striking risk of adverse events after TIA; however, there were no racial or gender differences predicting these events. Further study is warranted in interventions to prevent these adverse events after TIA. (Stroke. 2005;36:720-724.)

Author-supplied keywords

  • cerebral ischemia Ⅲ cerebral ischemia
  • transient Ⅲ epidemiology Ⅲ prognosis

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Dawn Kleindorfer

  • Peter Panagos

  • Arthur Pancioli

  • Jane Khoury

  • Brett Kissela

  • Daniel Woo

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free