Increase in the calcium level following anodal polarization in the rat brain

  • Islam N
  • Aftabuddin M
  • Moriwaki A
 et al. 
  • 109

    Readers

    Mendeley users who have this article in their library.
  • 106

    Citations

    Citations of this article.

Abstract

The accumulation of calcium ions (Ca) was examined in the rat brain by means of45Ca autoradiography following the application of a weak anodal direct current to the surface of the sensorimotor cortex. Repetition of the anodal polarization with 3.0 μA for 30 min caused more Ca to accumulate in the cerebral cortex. The degree and extent of accumulation was greater in the hemisphere ipsilateral to the polarization than in the other. Accumulation was also noted in the hippocampus and thalamus. Ca accumulation was detected after 24 h and it remained virtually constant up to 72 h after the last polarization. The results suggest that a long-lasting disturbance of Ca homeostasis is involved in the cortical plastic changes seen following anodal polarization. © 1995 Elsevier Science B.V. All rights reserved.

Author-supplied keywords

  • 45Ca autoradiography
  • Anodal polarization
  • Brain
  • Dark neuron
  • Direct current
  • Rat
  • Sensorimotor cortex

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Nadira Islam

  • Mohammad Aftabuddin

  • Akiyoshi Moriwaki

  • Yukio Hattori

  • Yasuo Hori

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free