Inhibition of class II histone deacetylases in the spinal cord attenuates inflammatory hyperalgesia

  • Bai G
  • Wei D
  • Zou S
 et al. 
  • 43


    Mendeley users who have this article in their library.
  • 81


    Citations of this article.


Several classes of histone deacetylases (HDACs) are expressed in the spinal cord that is a critical structure of the nociceptive pathway. HDAC-regulated histone acetylation is an important component of chromatin remodeling leading to epigenetic regulation of gene transcription. To understand the role of histone acetylation in epigenetic regulation of pathological pain, we have studied the impact of different classes of HDACs in the spinal cord on inflammatory hyperalgesia induced by complete Freund's adjuvant (CFA).

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text


  • Guang Bai

  • Dong Wei

  • Shiping Zou

  • Ke Ren

  • Ronald Dubner

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free