Injury among stimulant-treated youth with ADHD

  • Marcus S
  • Wan G
  • Zhang H
 et al. 
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Abstract

OBJECTIVE: To assess risk factors for injury among children and adolescents treated with stimulants for ADHD.

METHOD: An analysis was performed of pharmacy and service claims data from 2000-2003 California Medicaid (Medi-Cal) focusing on children and adolescents ages 6 to 17 years who initiated stimulant therapy for ADHD. Bivariate and multivariate analyses were performed to examine associations of demographic and clinical characteristics with injury.

RESULTS: In a Cox proportional hazard model that controlled for background patient characteristics, patients ages 13 to 17 years, male gender, prescription of anxiolytic/hypnotic medications, and diagnosis of a mood disorder were each independently associated with increased risk of injury, whereas African American ancestry and other minority racial/ethnic ancestry were associated with lower risk. Youth with high stimulant medication possession ratios (MPR) had a nonsignificantly lower risk of injury as compared to those with a low stimulant MPR.

CONCLUSION: These findings reveal several patient characteristics that may be associated with increased risk of injury among children and adolescents treated for ADHD.

Author-supplied keywords

  • ADHD
  • Injury
  • Stimulants

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Authors

  • Steven C. Marcus

  • George J. Wan

  • Huabin F. Zhang

  • Mark Olfson

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