In-situ fabrication of dialysis membranes in glass microchannels using laser-induced phase-separation polymerization

  • Kirby B
  • Singh A
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Abstract

Laser-induced phase-sepn. polymn. of a porous acrylate polymer is used for in-situ fabrication of dialysis membranes inside glass microchannels. A shaped 355 nm laser beam is used to define polymer membranes of 4-14 mm thickness, which bond to the glass microchannel and form a semipermeable membrane. Differential diffusion through the membrane is obsd. for fluorescein mols. vs. 200 nm latex microspheres, showing the potential for this technique to integrate sample cleanup into chip-based anal. systems. [on SciFinder (R)]

Author-supplied keywords

  • Dialysis
  • Dialyzers (membranes
  • Filtration
  • Lab-on-a-chip (in-situ fabrication of dialysis mem
  • in-situ fabrication of dialysis membranes in glass
  • membrane dialyzer pentaerythritol triacrylate poly

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Authors

  • Brian J Kirby

  • Anup K Singh

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